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Provedor de dados:  BJID
País:  Brazil
Título:  Clinical significance of different bacterial load ofMycoplasma pneumoniae in patients with Mycoplasma pneumoniae pneumonia
Autores:  Jiang,Wujun
Yan,Yongdong
Ji,Wei
Wang,Yuqing
Chen,Zhengrong
Data:  2014-04-01
Ano:  2014
Palavras-chave:  Mycoplasma pneumoniae
Pneumonia
Polymerase chain reaction
Serology
Resumo:  OBJECTIVE:This retrospective study was conducted to investigate the clinical significance of differentMycoplasma pneumoniae bacterial load in patients with M. pneumoniae pneumonia (MP) in children.METHODS:Patients with MP (n=511) were identified at the Children's Hospital Affiliated to Soochow University database during an outbreak of MP between January 2012 and February 2013.RESULTS:Comparing patients with high and low bacterial load those with higher loads were significantly older (p<0.01) and had fever significantly more frequently (p=0.01). Presence of wheezing at presentation was associated with low bacterial load (p=0.03). Baseline positive IgM was present in 93 (56.4%) patients with high bacterial load compared to 46 (27.8%) patients with low bacterial load (p<0.001). Co-infection with viruses was found significantly more frequent among patients with low bacterial load (24.2%) than those with high bacterial load (8.5%) [p<0.001]. Bacterial co-infection was also more frequently detected among patients with low bacterial load (22.4%) than in those with high bacterial load (12.1%) [p=0.01].CONCLUSION:M. pneumoniae at a high bacterial load could be an etiologic agent of respiratory tract disease, whereas the etiologic role of MP at a low bacterial load remains to be determined.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200124
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1016/j.bjid.2013.06.004
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.18 n.2 2014
Direitos:  info:eu-repo/semantics/openAccess
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